Trial intelligence / Profile preview

AVANZAR: datopotamab deruxtecan + durvalumab + carboplatin versus pembrolizumab + platinum-based chemotherapy in first-line advanced NSCLC

2021-004606-21Phase 3Active

Sponsor
AstraZeneca
Start
Aug 2022
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of datopotamab deruxtecan in non-small cell lung cancer (NSCLC) (2 arms), sponsored by AstraZeneca. Primary endpoint: Progression-free survival. Started Aug 2022; status: active.

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Drugs

datopotamab deruxtecan
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Conditions

non-small cell lung cancer (NSCLC)

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