Trial intelligence / Profile preview

LUNGVAC study of anti-PD-1/PD-L1 therapy with or without UV1 vaccination in first-line advanced NSCLC

2021-005729-25Phase 2Active

Sponsor
Vestre Viken Hospital Trust
Start
Nov 2021
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of UV1, pembrolizumab and sargramostim in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Vestre Viken Hospital Trust. Primary endpoint: Progression-free survival. Started Nov 2021; status: active.

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Drugs

UV1pembrolizumabsargramostim
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Conditions

non-small cell lung cancer (NSCLC)

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