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Sacituzumab govitecan plus pembrolizumab versus physician's choice chemotherapy plus pembrolizumab in previously untreated PD-L1-positive advanced or metastatic triple-negative breast cancer
2021-005742-14Phase 3Active
- Sponsor
- Gilead Sciences
- Start
- May 2022
- Modality
- Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial in triple-negative breast cancer (TNBC) comparing Sacituzumab govitecan + pembrolizumab with Treatment of physician's choice + pembrolizumab (2 arms). Primary endpoint: Progression-free survival. Started May 2022; status: active.
02
Drugs
sacituzumab govitecanpembrolizumab
03
Conditions
triple-negative breast cancer (TNBC)
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