Trial intelligence / Profile preview

Retifanlimab alone or with anti-LAG-3 and anti-TIM-3 in first-line PD-L1-positive recurrent/metastatic head and neck squamous cell carcinoma

2021-005775-39Phase 2Active

Sponsor
Incyte
Start
May 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in head and neck squamous cell carcinoma (HNSCC) comparing Retifanlimab alone, Retifanlimab + INCAGN02385 and Retifanlimab + INCAGN02385 + INCAGN02390 (3 arms). Primary endpoint: Progression-free survival. Started May 2022; status: active.

02

Drugs

retifanlimabtuparstobartverzistobart
03

Conditions

head and neck squamous cell carcinoma (HNSCC)

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