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Inotuzumab ozogamicin versus ALLR3 induction for pediatric high-risk first-relapse B-cell precursor acute lymphoblastic leukemia
2022-000186-40Phase 2Active
- Sponsor
- Pfizer
- Start
- Aug 2022
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 2, randomised, open-label trial of inotuzumab ozogamicin, mitoxantrone, vincristine, dexamethasone and pegaspargase in acute lymphoblastic leukemia (ALL) (2 arms), sponsored by Pfizer. Primary endpoint: MRD-negative CR/CRp/CRi at end of induction. Started Aug 2022; status: active.
02
Drugs
inotuzumab ozogamicinmitoxantronevincristinedexamethasonepegaspargase
03
Conditions
acute lymphoblastic leukemia (ALL)
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