Trial intelligence / Profile preview

GMALL-EVOLVE trial in newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia

2022-000760-21Phase 2Active

Sponsor
Goethe University Frankfurt
Start
Mar 2023
Modality
Small Molecules, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, scFv Fragments → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial of ponatinib, imatinib and blinatumomab in acute lymphoblastic leukemia (ALL) (4 arms), sponsored by Goethe University Frankfurt. Primary endpoint: Overall survival. Started Mar 2023; status: active.

02

Drugs

ponatinibimatinibblinatumomab
03

Conditions

acute lymphoblastic leukemia (ALL)

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