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Immune response kinetics and revaccination timing after anti-SARS-CoV-2 monoclonal antibodies in recovered COVID-19 patients

2022-000905-29Phase 4Active

Sponsor
National Institute for Infectious Diseases Lazzaro Spallanzani
Start
Mar 2022
Modality
Vaccines & Immunotherapeutics, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 4, open-label trial of tixagevimab + cilgavimab, sotrovimab, tozinameran, elasomeran and NVX-CoV2373 in coronavirus disease 2019 (COVID-19) (2 arms), sponsored by National Institute for Infectious Diseases Lazzaro Spallanzani. Primary endpoint: Effectiveness of revaccination at 4 versus 12 months. Started Mar 2022; status: active.

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Drugs

tixagevimab + cilgavimabsotrovimabtozinameranelasomeranNVX-CoV2373
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Conditions

coronavirus disease 2019 (COVID-19)

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