Trial intelligence / Profile preview

LORELY: Loncastuximab Tesirine after CAR T-cell failure in DLBCL/HGBCL

2022-001147-24Phase 2Active

Sponsor
Humanitas Research Hospital
Start
Jan 2023
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of loncastuximab tesirine in diffuse large B-cell lymphoma (DLBCL), large-cell lymphoma and mature B-cell lymphoma, sponsored by Humanitas Research Hospital. Primary endpoint: Overall response rate (ORR). Started Jan 2023; status: active.

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Drugs

loncastuximab tesirine
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Conditions

diffuse large B-cell lymphoma (DLBCL)large-cell lymphomamature B-cell lymphoma

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