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POLO study: combined effect of pregabalin or lacosamide with oxycodone on breathing in healthy volunteers
2022-001603-40Phase 4Completed
- Sponsor
- Leiden University Medical Center
- Start
- Jun 2022
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 4 trial of oxycodone, pregabalin and lacosamide (3 arms), sponsored by Leiden University Medical Center. Primary endpoint: Extrapolated end-tidal PCO2 at 55 mmHg (VE55) at 4 hours after oxycodone. Started Jun 2022; status: completed.
02
Drugs
oxycodonepregabalinlacosamide
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