Trial intelligence / Profile preview

Phase 2 study of SLN360 in participants with elevated lipoprotein(a) at high risk of ASCVD events

2022-001876-32Phase 2Completed

Sponsor
Silence Therapeutics
Start
Sep 2022
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in lipoprotein(a) hyperlipoproteinemia (Lp(a)) and atherosclerotic disease comparing SLN360 with Placebo (2 arms). Primary endpoint: Time-averaged change in Lp(a) from baseline to Week 36. Started Sep 2022; status: completed.

02

Drugs

zerlasiran
03

Conditions

lipoprotein(a) hyperlipoproteinemia (Lp(a))atherosclerotic disease

Beyond the preview

Go deeper on 2022-001876-32.

Study design, results and competitive context are available in the Gosset platform where reported.

Study design & results

Available in the Gosset platform where reported.

Competitive context

Available in the Gosset platform where reported.

Bring the full picture into focus.

See how Gosset can support your research on 2022-001876-32.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call