Trial intelligence / Profile preview

Phase 2 trial of nirmatrelvir/ritonavir in hospitalized high-risk or immunocompromised patients with severe COVID-19

2022-002447-22Phase 2Completed

Sponsor
Pfizer
Start
Sep 2022
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, double-blind trial in coronavirus disease 2019 (COVID-19) comparing Nirmatrelvir/ritonavir with Placebo/ritonavir (2 arms). Primary endpoint: Change from baseline in SARS-CoV-2 RNA level in nasopharyngeal swabs at Day 5. Started Sep 2022; status: completed.

02

Drugs

Nirmatrelvirritonavir
03

Conditions

coronavirus disease 2019 (COVID-19)

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