Trial intelligence / Profile preview

TROPIONBreast03 in residual triple-negative breast cancer after neoadjuvant therapy

2022-002680-30Phase 3Active

Sponsor
AstraZeneca
Start
Oct 2022
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 3, randomised, open-label trial of datopotamab deruxtecan, durvalumab, capecitabine and pembrolizumab in triple-negative breast cancer (TNBC) (3 arms), sponsored by AstraZeneca. Primary endpoint: Invasive disease-free survival. Started Oct 2022; status: active.

02

Drugs

datopotamab deruxtecandurvalumabcapecitabinepembrolizumab
03

Conditions

triple-negative breast cancer (TNBC)

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