Trial intelligence / Profile preview

Paclitaxel + carboplatin + maintenance letrozole versus letrozole monotherapy in primary low-grade serous ovarian or peritoneal carcinoma

2022-002877-27Phase 3Active

Sponsor
Cancer Trials Ireland
Start
Jan 2023
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised trial in Serous Papillary Cystadenocarcinoma and serous peritoneal carcinoma (PPSC) comparing Paclitaxel + carboplatin followed by maintenance letrozole with Letrozole monotherapy (2 arms). Primary endpoint: Progression-free survival. Started Jan 2023; status: active.

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Drugs

letrozolepaclitaxelcarboplatin
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Conditions

Serous Papillary Cystadenocarcinomaserous peritoneal carcinoma (PPSC)

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