Trial intelligence / Profile preview

Phase 2 study of rituximab + polatuzumab vedotin + glofitamab in older untreated aggressive B-cell lymphoma patients ineligible for full-dose R-CHOP

2022-003398-51Phase 2Active

Sponsor
Institut für Klinische Krebsforschung
Start
Jan 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
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Overview

Phase 2, open-label, single-arm trial of rituximab, polatuzumab vedotin and glofitamab in diffuse large B-cell lymphoma (DLBCL), sponsored by Institut für Klinische Krebsforschung. Primary endpoint: 1-year progression-free survival rate. Started Jan 2023; status: active.

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Drugs

rituximabpolatuzumab vedotinglofitamab
03

Conditions

diffuse large B-cell lymphoma (DLBCL)

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