Trial intelligence / Profile preview

DUMELEP: Durvalumab + Tremelimumab peri-procedural therapy with electroporation ablation in BCLC A hepatocellular carcinoma

2022-003561-38Phase 2Active

Sponsor
Assistance publique - Hôpitaux de Paris
Start
Jan 2023
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, single-arm trial of durvalumab and tremelimumab in hepatocellular carcinoma (HCC), sponsored by Assistance publique - Hôpitaux de Paris. Primary endpoint: Local recurrence-free survival at 1 year. Started Jan 2023; status: active.

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Drugs

durvalumabtremelimumab
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Conditions

hepatocellular carcinoma (HCC)

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