Trial intelligence / Profile preview

Discontinuation of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia

2022-004165-20Phase 3Active

Sponsor
CHU de Poitiers
Start
Jan 2023
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of imatinib, nilotinib, dasatinib and bosutinib in chronic myelogenous leukemia (CML) (2 arms), sponsored by CHU de Poitiers. Primary endpoint: Treatment-free remission at 24 months. Started Jan 2023; status: active.

02

Drugs

imatinibnilotinibdasatinibbosutinib
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Conditions

chronic myelogenous leukemia (CML)

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