Trial intelligence / Profile preview

LUPUS: Neoadjuvant intra-arterial [177Lu]Lu-PSMA-617 before radical prostatectomy in high-risk localized or locally advanced prostate cancer

2022-500838-28-00Phase 2Authorised

Sponsor
Universitätsmedizin Essen
Start
Nov 2023
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptide-Drug Conjugates → Peptide Conjugates → Peptides, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of lutetium lu 177 vipivotide tetraxetan in prostate cancer (PCa), sponsored by Universitätsmedizin Essen. Primary endpoints: Adverse Events related to intra-arterial [177Lu]Lu-PSMA-617 therapy and Delay of scheduled surgery due to AEs. Planned start Nov 2023; status: authorised.

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Drugs

lutetium lu 177 vipivotide tetraxetan
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Conditions

prostate cancer (PCa)

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