Trial intelligence / Profile preview

RELATIVITY-127 subcutaneous versus intravenous nivolumab + relatlimab in untreated unresectable or metastatic melanoma

2022-500967-11-00Phase 3Authorised

Sponsor
Bristol Myers Squibb
Start
Jul 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Therapeutic Enzymes → Recombinant Proteins and Enzymes
Countries
22
01

Overview

Phase 3, randomised, open-label trial of nivolumab, relatlimab and ENHANZE in melanoma (2 arms), sponsored by Bristol Myers Squibb. Primary endpoints: Pharmacokinetic non-inferiority of subcutaneous versus intravenous nivolumab and Pharmacokinetic non-inferiority of subcutaneous versus intravenous relatlimab. Planned start Jul 2023; status: authorised.

02

Drugs

nivolumabrelatlimabENHANZE
03

Conditions

melanoma

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