Trial intelligence / Profile preview

UNICORN study

2022-501308-90-00Phase 2Authorised

Sponsor
G.O.N.O. - Gruppo Oncologico del Nord Ovest
Start
Apr 2023
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, open-label trial of botensilimab, sotorasib, trastuzumab deruxtecan, durvalumab, nivolumab and 4 more in colorectal cancer (CRC) (10 cohorts), sponsored by G.O.N.O. - Gruppo Oncologico del Nord Ovest. Primary endpoint: Major pathological response rate. Planned start Apr 2023; status: authorised.

02

Drugs

botensilimabsotorasibtrastuzumab deruxtecandurvalumabnivolumab
03

Conditions

colorectal cancer (CRC)

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