Trial intelligence / Profile preview

LINKER-MM3: linvoseltamab versus elotuzumab + pomalidomide + dexamethasone in relapsed/refractory multiple myeloma

2022-501396-62-00Phase 3Authorised

Sponsor
Regeneron Pharmaceuticals
Start
Sep 2023
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Molecular Glues → Targeted Protein Degraders (TPDs) → Small Molecules, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
17
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Overview

Phase 3, randomised, open-label trial in multiple myeloma (MM) comparing Linvoseltamab with Elotuzumab + pomalidomide + dexamethasone (2 arms). Primary endpoint: Progression-free survival in CD38 antibody exposed participants. Planned start Sep 2023; status: authorised.

02

Drugs

linvoseltamabelotuzumabpomalidomidedexamethasone
03

Conditions

multiple myeloma (MM)

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