Trial intelligence / Profile preview

J3L-MC-EZEB Phase 2 Study of LY3819469 in Adults with Elevated Lipoprotein(a)

2022-501426-38-00Phase 2Completed

Sponsor
Eli Lilly and Company
Start
Jan 2023
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
10
01

Overview

Phase 2, randomised, double-blind trial in lipoprotein(a) hyperlipoproteinemia (Lp(a)) comparing LY3819469 with Placebo (2 arms). Primary endpoint: Percent change from baseline in time-averaged Lp(a) over Days 60-180. Started Jan 2023; status: completed.

02

Drugs

lepodisiran
03

Conditions

lipoprotein(a) hyperlipoproteinemia (Lp(a))

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