Trial intelligence / Profile preview

LEAP-008: pembrolizumab + lenvatinib versus docetaxel in previously treated metastatic NSCLC

2022-501439-18-00Phase 3Completed

Sponsor
Merck & Co.
Start
Jun 2023
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
18
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Overview

Phase 3, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Pembrolizumab + lenvatinib, Lenvatinib monotherapy and Docetaxel (3 arms). Primary endpoints: Overall Survival and Progression-free Survival per RECIST 1.1. Started Jun 2023; status: completed.

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Drugs

pembrolizumablenvatinibdocetaxel
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Conditions

non-small cell lung cancer (NSCLC)

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