Trial intelligence / Profile preview

INSTA-MD in treatment-resistant major depressive disorder

2022-501692-35-00Phase 3Authorised

Sponsor
University of Antwerp
Start
Sep 2023
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial in major depressive disorder (MDD) comparing Celecoxib augmentation, Minocycline augmentation and Placebo augmentation (3 arms). Primary endpoints: Change in HDRS-17 score and Remission rate by HDRS-17. Planned start Sep 2023; status: authorised.

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Drugs

celecoxibminocycline
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Conditions

major depressive disorder (MDD)

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