Trial intelligence / Profile preview

HERMES ziltivekimab in inflammatory HFpEF/HFmrEF

2022-501939-16-00Phase 3Authorised

Sponsor
Novo Nordisk
Start
May 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
46
01

Overview

Phase 3, randomised, double-blind trial in heart failure with preserved ejection fraction (HFpEF) and heart failure with mid-range ejection fraction (HFmrEF) comparing ziltivekimab with placebo (2 arms). Primary endpoints: Time to first occurrence of composite heart failure endpoint and Total number of cardiovascular death and heart failure events. Planned start May 2023; status: authorised.

02

Drugs

ziltivekimab
03

Conditions

heart failure with preserved ejection fraction (HFpEF)heart failure with mid-range ejection fraction (HFmrEF)

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