Trial intelligence / Profile preview

Phase 1/2 Randomized Double-blind Placebo-controlled Study of AOC 1020 in Adults with Facioscapulohumeral Muscular Dystrophy

2022-502096-32-00Phase 2Completed

Sponsor
Avidity Biosciences
Start
Jul 2023
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
5
01

Overview

Phase 2, randomised, double-blind trial in facioscapulohumeral muscular dystrophy (FSHD) comparing AOC 1020 with Placebo (2 arms). Primary endpoint: Incidence of treatment-emergent adverse events. Started Jul 2023; status: completed.

02

Drugs

delpacibart braxlosiran
03

Conditions

facioscapulohumeral muscular dystrophy (FSHD)

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