Trial intelligence / Profile preview

VULCANize2: Chemoradiation vs neoadjuvant chemotherapy plus surgery in locally advanced vulvar cancer

2022-502685-25-00Phase 3Authorised

Sponsor
Netherlands Cancer Institute
Start
Jan 2024
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
4
01

Overview

Phase 3, randomised, open-label trial of carboplatin, paclitaxel and cisplatin in vulvar squamous cell carcinoma (VSCC) (2 arms), sponsored by Netherlands Cancer Institute. Primary endpoint: Loco-regional control at 2 years. Planned start Jan 2024; status: authorised.

02

Drugs

carboplatinpaclitaxelcisplatin
03

Conditions

vulvar squamous cell carcinoma (VSCC)

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