Trial intelligence / Profile preview

MetroWILMS-1906 metronomic chemotherapy for relapsed or refractory Wilms tumor

2022-502687-20-00Phase 2Authorised

Sponsor
Centre Oscar Lambret
Start
Sep 2022
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of vinblastine, isotretinoin, temozolomide, etoposide, irinotecan and 1 more in Wilms' tumor, sponsored by Centre Oscar Lambret. Primary endpoints: Dose-limiting toxicity and Disease control after 2 cycles. Planned start Sep 2022; status: authorised.

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Drugs

vinblastineisotretinointemozolomideetoposideirinotecan
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Conditions

Wilms' tumor

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