Trial intelligence / Profile preview

Rituximab B-cell depletion pilot study in amyotrophic lateral sclerosis

2022-502743-35-00Phase 2Authorised

Sponsor
German Center for Neurodegenerative Diseases
Start
Apr 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, double-blind trial in amyotrophic lateral sclerosis (ALS) comparing Rituximab + riluzole with Placebo + riluzole (2 arms). Primary endpoint: Change in ALS Functional Rating Scale - Revised self-explanatory version. Planned start Apr 2024; status: authorised.

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Drugs

rituximab
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Conditions

amyotrophic lateral sclerosis (ALS)

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