Trial intelligence / Profile preview

Morpheus-Neo HCC neoadjuvant immunotherapy combinations in resectable hepatocellular carcinoma

2022-502840-11-00Phase 2Completed

Sponsor
Roche
Start
Nov 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
10
01

Overview

Phase 2, randomised, open-label trial in hepatocellular carcinoma (HCC) comparing Neoadjuvant Tecentriq + Avastin, Neoadjuvant Tecentriq + tiragolumab and Neoadjuvant Tecentriq + RO7247669 (3 arms). Primary endpoint: MPR rate. Started Nov 2023; status: completed.

02

Drugs

atezolizumabbevacizumabtiragolumabtobemstomig
03

Conditions

hepatocellular carcinoma (HCC)

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