Trial intelligence / Profile preview

Nivolumab plus ipilimumab vs ipilimumab vs cabazitaxel in metastatic castration-resistant prostate cancer

2022-502909-15-00Phase 2Completed

Sponsor
Bristol Myers Squibb
Start
Aug 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
4
01

Overview

Phase 2, randomised trial in metastatic castration-resistant prostate cancer (mCRPC) comparing Nivolumab plus ipilimumab, Ipilimumab monotherapy and Cabazitaxel plus prednisone (3 arms). Primary endpoints: Objective Response Rate in Cohorts B, C, and D and Radiographic Progression-Free Survival. Started Aug 2023; status: completed.

02

Drugs

nivolumabipilimumabcabazitaxel
03

Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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