Trial intelligence / Profile preview

Long-term Safety and Clinical Activity Extension Study of mRNA-3927 in Propionic Acidemia

2022-502911-12-00Phase 2Authorised

Sponsor
Moderna Inc
Start
Feb 2026
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Countries
8
01

Overview

Phase 2, open-label, single-arm trial of mRNA-3927 in propionic acidemia (PA), sponsored by Moderna Inc. Primary endpoint: Incidence and severity of adverse events. Planned start Feb 2026; status: authorised.

02

Drugs

mRNA-3927
03

Conditions

propionic acidemia (PA)

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