Trial intelligence / Profile preview

Zimberelimab + Domvanalimab vs Pembrolizumab in First-Line PD-L1-High Metastatic NSCLC

2022-503071-28-00Phase 3Completed

Sponsor
Arcus Biosciences
Start
Aug 2023
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
22
01

Overview

Phase 3, randomised trial in non-small cell lung cancer (NSCLC) comparing Zimberelimab + Domvanalimab with Pembrolizumab (2 arms). Primary endpoint: Overall survival. Started Aug 2023; status: completed.

02

Drugs

pembrolizumabzimberelimabdomvanalimab
03

Conditions

non-small cell lung cancer (NSCLC)

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