Trial intelligence / Profile preview

UMBRELLA trial of tislelizumab in patients with molecular residual disease after curative treatment

2023-503316-33-00Phase 3Authorised

Sponsor
Gustave Roussy
Start
Mar 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC), colorectal cancer (CRC), pancreatic cancer (PC) and 1 more comparing Tislelizumab with Placebo / saline control (2 arms). Primary endpoint: Disease-free survival in MRD-positive patients. Planned start Mar 2024; status: authorised.

02

Drugs

tislelizumab
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Conditions

non-small cell lung cancer (NSCLC)colorectal cancer (CRC)pancreatic cancer (PC)soft tissue sarcoma (STS)

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