Trial intelligence / Profile preview

CARE1 first-line randomized platform study in metastatic renal cell carcinoma

2023-503317-29-00Phase 3Authorised

Sponsor
Gustave Roussy
Start
Apr 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
12
01

Overview

Phase 3, randomised, open-label trial of pembrolizumab, nivolumab, ipilimumab, axitinib, lenvatinib and 1 more in renal cell carcinoma (RCC) (4 arms), sponsored by Gustave Roussy. Primary endpoints: Overall survival, Progression-free survival and 6 more. Planned start Apr 2024; status: authorised.

02

Drugs

pembrolizumabnivolumabipilimumabaxitiniblenvatinib
03

Conditions

renal cell carcinoma (RCC)

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