Trial intelligence / Profile preview

ILLUMINATE-C

2023-503382-29-00Phase 3Completed

Sponsor
Alnylam Pharmaceuticals
Start
May 2023
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
12
01

Overview

Phase 3, open-label trial of lumasiran in Primary Hyperoxaluria Type 1 (PH1) (2 cohorts), sponsored by Alnylam Pharmaceuticals. Primary endpoints: Cohort A: Percent change in plasma oxalate from baseline to Month 6 and Cohort B: Percent change in plasma oxalate from baseline to Month 6. Started May 2023; status: completed.

02

Drugs

lumasiran
03

Conditions

Primary Hyperoxaluria Type 1 (PH1)

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