Trial intelligence / Profile preview

Teclistamab- or talquetamab-based triplets versus DRd in transplant-ineligible or transplant-deferred newly diagnosed multiple myeloma

2023-503442-30-00Phase 3Authorised

Sponsor
Janssen Pharmaceutical
Start
Oct 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
26
01

Overview

Phase 3, randomised trial of teclistamab, talquetamab, daratumumab, lenalidomide and dexamethasone in multiple myeloma (MM) (3 arms), sponsored by Janssen Pharmaceutical. Primary endpoints: Progression-free survival and 12-month MRD-negative complete response. Planned start Oct 2022; status: authorised.

02

Drugs

teclistamabtalquetamabdaratumumablenalidomidedexamethasone
03

Conditions

multiple myeloma (MM)

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