Trial intelligence / Profile preview

Phase 1/2 study of BMS-986449 alone and with nivolumab in advanced solid tumors

2023-503484-42-00Phase 2Authorised

Sponsor
Bristol Myers Squibb
Start
Oct 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Molecular Glues → Targeted Protein Degraders (TPDs) → Small Molecules
Countries
6
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Overview

Phase 2, open-label trial of BMS-986449 and nivolumab in Nonhematologic neoplasms, non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC) (3 arms), sponsored by Bristol Myers Squibb. Primary endpoint: Safety and dose-limiting toxicities. Planned start Oct 2023; status: authorised.

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Drugs

BMS-986449nivolumab
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Conditions

Nonhematologic neoplasmsnon-small cell lung cancer (NSCLC)triple-negative breast cancer (TNBC)

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