Trial intelligence / Profile preview

CRN04894 in Congenital Adrenal Hyperplasia

2023-503488-40-00Phase 2Completed

Sponsor
Crinetics Pharmaceuticals
Start
Nov 2023
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
7
01

Overview

Phase 2, open-label, single-arm trial of atumelnant in 21-hydroxylase deficiency (21-OHD), sponsored by Crinetics Pharmaceuticals. Primary endpoints: Incidence of treatment-emergent adverse events (TEAEs) and Change from baseline in morning serum androstenedione (A4) at Week 12. Started Nov 2023; status: completed.

02

Drugs

atumelnant
03

Conditions

21-hydroxylase deficiency (21-OHD)

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