Trial intelligence / Profile preview

DESTINY-Lung04 first-line trastuzumab deruxtecan in HER2-mutated NSCLC

2023-503674-20-00Phase 3Authorised

Sponsor
AstraZeneca
Start
Dec 2021
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
20
01

Overview

Phase 3, randomised, open-label trial of trastuzumab deruxtecan in non-small cell lung cancer (NSCLC) (2 arms), sponsored by AstraZeneca. Primary endpoint: Progression-free survival by BICR. Planned start Dec 2021; status: authorised.

02

Drugs

trastuzumab deruxtecan
03

Conditions

non-small cell lung cancer (NSCLC)

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