Trial intelligence / Profile preview

Relatlimab plus Nivolumab in Pediatric and Young Adult Relapsed/Refractory Lymphoma (RELATIVITY-069)

2023-503715-14-00Phase 2Completed

Sponsor
Bristol Myers Squibb
Start
Aug 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
7
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Overview

Phase 2, open-label trial of relatlimab and nivolumab in classical Hodgkin lymphoma (cHL), non-Hodgkin lymphoma (NHL), primary mediastinal large B-cell lymphoma (PMBCL) and 7 more (3 arms), sponsored by Bristol Myers Squibb. Primary endpoints: Dose-limiting toxicities (DLTs), MTD/RP2D, and safety profile in Part A, Pharmacokinetics of relatlimab in Part A and 1 more. Started Aug 2023; status: completed.

02

Drugs

relatlimabnivolumab
03

Conditions

classical Hodgkin lymphoma (cHL)non-Hodgkin lymphoma (NHL)primary mediastinal large B-cell lymphoma (PMBCL)diffuse large B-cell lymphoma (DLBCL)mediastinal gray zone lymphoma (GZL)

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