Trial intelligence / Profile preview

SLURP: Fluorescence molecular endoscopy with oral and topical bevacizumab-800CW and cetuximab-800CW in Barrett's esophagus

2023-503801-12-00Phase 2Completed

Sponsor
University Medical Center Groningen
Start
May 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of bevacizumab and cetuximab in Barrett's esophagus, esophageal adenocarcinoma (EAC) and esophageal dysplasia, sponsored by University Medical Center Groningen. Primary endpoints: Feasibility and safety of oral tracer administration and Effect of combined tracer administration on lesion detection. Started May 2023; status: completed.

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Drugs

bevacizumabcetuximab
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Conditions

Barrett's esophagusesophageal adenocarcinoma (EAC)esophageal dysplasia

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