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EXPAND: ALLO-647 added to fludarabine/cyclophosphamide lymphodepletion before ALLO-501A in relapsed/refractory large B-cell lymphoma

2023-503830-27-00Phase 2Completed

Sponsor
Allogene Therapeutics
Start
Aug 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
Countries
5
01

Overview

Phase 2, randomised, open-label trial of cemacabtagene ansegedleucel and allo-647 in diffuse large B-cell lymphoma (DLBCL) (2 arms), sponsored by Allogene Therapeutics. Primary endpoint: Progression-free survival. Started Aug 2023; status: completed.

02

Drugs

cemacabtagene ansegedleucelallo-647
03

Conditions

diffuse large B-cell lymphoma (DLBCL)

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