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Obinutuzumab + venetoclax versus obinutuzumab + chlorambucil in previously untreated CLL with coexisting medical conditions

2023-504034-22-00Phase 3Completed

Sponsor
Roche
Start
Dec 2014
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
22
01

Overview

Phase 3, randomised, open-label trial in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) comparing Obinutuzumab + venetoclax with Obinutuzumab + chlorambucil (2 arms). Primary endpoint: Progression-free survival. Started Dec 2014; status: completed.

02

Drugs

obinutuzumabvenetoclaxchlorambucil
03

Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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