Trial intelligence / Profile preview

ASPIRE-1: Endothelin receptor antagonist SC0062 with dapagliflozin in T1DM and CKD

2023-504404-28-00Phase 2Withdrawn

Sponsor
University Medical Center Groningen
Start
Feb 2026
Modality
Small Molecules
Countries
3
01

Overview

Phase 2, randomised, open-label trial of dapagliflozin and SC0062 in chronic kidney disease (CKD) and diabetes mellitus type 1 (T1D), sponsored by University Medical Center Groningen. Primary endpoint: Change from baseline in urine albumin-creatinine ratio (UACR) with SC0062 alone versus combination of dapagliflozin and SC0062. Planned start Feb 2026; status: withdrawn.

02

Drugs

dapagliflozinSC0062
03

Conditions

chronic kidney disease (CKD)diabetes mellitus type 1 (T1D)

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