Trial intelligence / Profile preview

Perioperative sacituzumab govitecan + zimberelimab + domvanalimab in cisplatin-ineligible muscle-invasive bladder cancer

2023-504420-26-00Phase 2Authorised

Sponsor
Fundación para el Progreso de la Oncología en Cantabria
Start
Jan 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of sacituzumab govitecan, zimberelimab and domvanalimab in bladder cancer and transitional cell carcinoma (TCC), sponsored by Fundación para el Progreso de la Oncología en Cantabria. Primary endpoint: Pathologic complete response rate. Planned start Jan 2025; status: authorised.

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Drugs

sacituzumab govitecanzimberelimabdomvanalimab
03

Conditions

bladder cancertransitional cell carcinoma (TCC)

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Available in the Gosset platform where reported.

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