Trial intelligence / Profile preview

C5731005 Phase 2 Basket Study of Disitamab Vedotin in HER2-Expressing Solid Tumors

2023-504445-31-00Phase 2Authorised

Sponsor
Seagen Inc.
Start
Sep 2024
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
10
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Overview

Phase 2, open-label, single-arm trial of disitamab vedotin in head and neck cancer (HNC), non-small cell lung cancer (NSCLC), Ovarian Epithelial Adenocarcinoma and 3 more, sponsored by Seagen Inc. Primary endpoint: Confirmed objective response rate (ORR) per RECIST v1.1. Planned start Sep 2024; status: authorised.

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Drugs

disitamab vedotin
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Conditions

head and neck cancer (HNC)non-small cell lung cancer (NSCLC)Ovarian Epithelial Adenocarcinomafallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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