Trial intelligence / Profile preview

Phase 3 trial of epcoritamab versus investigator's choice chemotherapy in relapsed or refractory diffuse large B-cell lymphoma

2023-504830-23-00Phase 3Authorised

Sponsor
Genmab
Start
Feb 2024
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
25
01

Overview

Phase 3, randomised, open-label trial of epcoritamab in diffuse large B-cell lymphoma (DLBCL), large-cell lymphoma, follicular lymphoma (FL) and 2 more (2 arms), sponsored by Genmab. Primary endpoints: Overall survival and Progression-free survival by independent review. Planned start Feb 2024; status: authorised.

02

Drugs

epcoritamab
03

Conditions

diffuse large B-cell lymphoma (DLBCL)large-cell lymphomafollicular lymphoma (FL)T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL)mature B-cell lymphoma

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