Trial intelligence / Profile preview

MK-2870 versus platinum doublet chemotherapy in EGFR-mutated advanced nonsquamous NSCLC after prior EGFR TKI

2023-504910-31-00Phase 3Authorised

Sponsor
Merck & Co.
Start
Jul 2024
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
19
01

Overview

Phase 3, randomised, open-label trial of sacituzumab tirumotecan, pemetrexed and carboplatin in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Merck & Co. Primary endpoint: Overall survival. Planned start Jul 2024; status: authorised.

02

Drugs

sacituzumab tirumotecanpemetrexedcarboplatin
03

Conditions

non-small cell lung cancer (NSCLC)

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