Trial intelligence / Profile preview

KeyForm-010

2023-505022-34-00Phase 2Completed

Sponsor
Merck & Co.
Start
Oct 2023
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
10
01

Overview

Phase 2, randomised, double-blind trial of pembrolizumab, favezelimab, lenvatinib and favezelimab + pembrolizumab in cutaneous squamous cell carcinoma (cSCC), endometrial cancer (EC) and cancer (4 cohorts), sponsored by Merck & Co. Primary endpoints: Clinical Benefit - Cohort A and Objective Response Rate (ORR) per RECIST 1.1 as assessed by Investigator – Cohort B. Started Oct 2023; status: completed.

02

Drugs

pembrolizumabfavezelimablenvatinibfavezelimab + pembrolizumab
03

Conditions

cutaneous squamous cell carcinoma (cSCC)endometrial cancer (EC)cancer

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