Trial intelligence / Profile preview

PRODIGE 88-CIRCULATE PAC

2023-505046-26-00Phase 3Authorised

Sponsor
Centre Hospitalier Universitaire Dijon Bourgogne
Start
May 2026
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of trifluridine + tipiracil, irinotecan, fluorouracil, folinic acid and bevacizumab in colorectal cancer (CRC), colon adenocarcinoma and rectal adenocarcinoma (2 arms), sponsored by Centre Hospitalier Universitaire Dijon Bourgogne. Primary endpoint: Time to recurrence. Planned start May 2026; status: authorised.

02

Drugs

trifluridine + tipiracilirinotecanfluorouracilfolinic acidbevacizumab
03

Conditions

colorectal cancer (CRC)colon adenocarcinomarectal adenocarcinoma

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